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T-regulatory cell treatment prevents chronic rejection of heart allografts in a murine mixed chimerism model

BACKGROUND: The mixed chimerism approach induces donor-specific tolerance in both pre-clinical models and clinical pilot trials. However, chronic rejection of heart allografts and acute rejection of skin allografts were observed in some chimeric animals despite persistent hematopoietic chimerism and...

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Autores principales:	Pilat, Nina, Farkas, Andreas M., Mahr, Benedikt, Schwarz, Christoph, Unger, Lukas, Hock, Karin, Oberhuber, Rupert, Aumayr, Klaus, Wrba, Fritz, Wekerle, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991417/ https://www.ncbi.nlm.nih.gov/pubmed/24468120 http://dx.doi.org/10.1016/j.healun.2013.11.004

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