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Orexin-A Promotes Cell Migration in Cultured Rat Astrocytes via Ca(2+)-Dependent PKCα and ERK1/2 Signals

Orexin-A is an important neuropeptide involved in the regulation of feeding, arousal, energy consuming, and reward seeking in the body. The effects of orexin-A have widely studied in neurons but not in astrocytes. Here, we report that OX1R and OX2R are expressed in cultured rat astrocytes. Orexin-A...

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Detalles Bibliográficos
Autores principales: Shu, Qing, Hu, Zhuang-Li, Huang, Chao, Yu, Xiao-Wei, Fan, Hua, Yang, Jing-Wen, Fang, Peng, Ni, Lan, Chen, Jian-Guo, Wang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991588/
https://www.ncbi.nlm.nih.gov/pubmed/24748172
http://dx.doi.org/10.1371/journal.pone.0095259