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A Three Step Network Based Approach (TSNBA) to Finding Disease Molecular Signature and Key Regulators: A Case Study of IL-1 and TNF-Alpha Stimulated Inflammation

A disease molecular signature is a set of biomolecular features that are prognostic of clinical phenotypes and indicative of underlying pathology. It is of great importance to develop computational approaches for finding more relevant molecular signatures. Based upon the hypothesis that various comp...

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Detalles Bibliográficos
Autores principales: Yang, Jihong, Li, Zheng, Fan, Xiaohui, Cheng, Yiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991618/
https://www.ncbi.nlm.nih.gov/pubmed/24747419
http://dx.doi.org/10.1371/journal.pone.0094360