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IFNL4 ss469415590 Variant Shows Similar Performance to rs12979860 as Predictor of Response to Treatment against Hepatitis C Virus Genotype 1 or 4 in Caucasians
OBJECTIVES: The rs12979860 variant, linked to IL28B gene, predicts sustained viral response (SVR) to pegylated-interferon/ribavirin (pegIFN/RBV) therapy in Hepatitis C Virus genotype 1 or 4 (HCV-1/4)-infected patients. Recently, a functional variant, ss469415590, in linkage disequilibrium (LD) with...
Autores principales: | Real, Luis M., Neukam, Karin, Herrero, Rocío, Guardiola, Josep M., Reiberger, Thomas, Rivero-Juarez, Antonio, Salazar, Juliana, Mandorfer, Mattias, Merino, Dolores, Soriano, Vicente, Rivero, Antonio, Macías, Juan, Pineda, Juan A., Caruz, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991683/ https://www.ncbi.nlm.nih.gov/pubmed/24748394 http://dx.doi.org/10.1371/journal.pone.0095515 |
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