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Interpreting Frequency Responses to Dose-Conserved Pulsatile Input Signals in Simple Cell Signaling Motifs
Many hormones are released in pulsatile patterns. This pattern can be modified, for instance by changing pulse frequency, to encode relevant physiological information. Often other properties of the pulse pattern will also change with frequency. How do signaling pathways of cells targeted by these ho...
Autores principales: | Fletcher, Patrick A., Clément, Frédérique, Vidal, Alexandre, Tabak, Joel, Bertram, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991699/ https://www.ncbi.nlm.nih.gov/pubmed/24748217 http://dx.doi.org/10.1371/journal.pone.0095613 |
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