Genome-Wide Analysis of Loss of Heterozygosity in Breast Infiltrating Ductal Carcinoma Distant Normal Tissue Highlights Arm Specific Enrichment and Expansion across Tumor Stages

Studies have shown concurrent loss of heterozygosity (LOH) in breast infiltrating ductal carcinoma (IDC) and adjacent or distant normal tissue. However, the overall extent of LOH in normal tissue and their significance to tumorigenesis remain unknown, as existing studies are largely based on selecte...

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Detalles Bibliográficos
Autores principales: Ruan, Xiaoyang, Liu, Hongfang, Boardman, Lisa, Kocher, Jean-Pierre A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991715/
https://www.ncbi.nlm.nih.gov/pubmed/24748104
http://dx.doi.org/10.1371/journal.pone.0095783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991715/
https://www.ncbi.nlm.nih.gov/pubmed/24748104
http://dx.doi.org/10.1371/journal.pone.0095783

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