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Characteristics, In-Hospital and Long-Term Clinical Outcomes of Nonagenarian Compared with Octogenarian Acute Myocardial Infarction Patients

We compared clinical characteristics, management, and clinical outcomes of nonagenarian acute myocardial infarction (AMI) patients (n=270, 92.3±2.3 yr old) with octogenarian AMI patients (n=2,145, 83.5±2.7 yr old) enrolled in Korean AMI Registry (KAMIR). Nonagenarians were less likely to have hypert...

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Autores principales: Lee, Ki Hong, Ahn, Youngkeun, Kim, Sung Soo, Rhew, Si Hyun, Jeong, Young Wook, Jang, Soo Young, Cho, Jae Yeong, Jeong, Hae Chang, Park, Keun-Ho, Yoon, Nam Sik, Sim, Doo Sun, Yoon, Hyun Joo, Kim, Kye Hun, Hong, Young Joon, Park, Hyung Wook, Kim, Ju Han, Cho, Jeong Gwan, Park, Jong Chun, Jeong, Myung Ho, Cho, Myeong-Chan, Kim, Chong Jin, Kim, Young Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991796/
https://www.ncbi.nlm.nih.gov/pubmed/24753700
http://dx.doi.org/10.3346/jkms.2014.29.4.527
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author Lee, Ki Hong
Ahn, Youngkeun
Kim, Sung Soo
Rhew, Si Hyun
Jeong, Young Wook
Jang, Soo Young
Cho, Jae Yeong
Jeong, Hae Chang
Park, Keun-Ho
Yoon, Nam Sik
Sim, Doo Sun
Yoon, Hyun Joo
Kim, Kye Hun
Hong, Young Joon
Park, Hyung Wook
Kim, Ju Han
Cho, Jeong Gwan
Park, Jong Chun
Jeong, Myung Ho
Cho, Myeong-Chan
Kim, Chong Jin
Kim, Young Jo
author_facet Lee, Ki Hong
Ahn, Youngkeun
Kim, Sung Soo
Rhew, Si Hyun
Jeong, Young Wook
Jang, Soo Young
Cho, Jae Yeong
Jeong, Hae Chang
Park, Keun-Ho
Yoon, Nam Sik
Sim, Doo Sun
Yoon, Hyun Joo
Kim, Kye Hun
Hong, Young Joon
Park, Hyung Wook
Kim, Ju Han
Cho, Jeong Gwan
Park, Jong Chun
Jeong, Myung Ho
Cho, Myeong-Chan
Kim, Chong Jin
Kim, Young Jo
author_sort Lee, Ki Hong
collection PubMed
description We compared clinical characteristics, management, and clinical outcomes of nonagenarian acute myocardial infarction (AMI) patients (n=270, 92.3±2.3 yr old) with octogenarian AMI patients (n=2,145, 83.5±2.7 yr old) enrolled in Korean AMI Registry (KAMIR). Nonagenarians were less likely to have hypertension, diabetes and less likely to be prescribed with beta-blockers, statins, and glycoprotein IIb/IIIa inhibitors compared with octogenarians. Although percutaneous coronary intervention (PCI) was preferred in octogenarians than nonagenarians, the success rate of PCI between the two groups was comparable. In-hospital mortality, the composite of in-hospital adverse outcomes and one year mortality were higher in nonagenarians than in octogenarians. However, the composite of the one year major adverse cardiac events (MACEs) was comparable between the two groups without differences in MI or re-PCI rate. PCI improved 1-yr mortality (adjusted hazard ratio [HR], 0.50; 95% confidence interval [CI], 0.36-0.69, P<0.001) and MACEs (adjusted HR, 0.47; 95% CI, 0.37-0.61, P<0.001) without significant complications both in nonagenarians and octogenarians. In conclusion, nonagenarians had similar 1-yr MACEs rates despite of higher in-hospital and 1-yr mortality compared with octogenarian AMI patients. PCI in nonagenarian AMI patients was associated to better 1-yr clinical outcomes. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-39917962014-04-21 Characteristics, In-Hospital and Long-Term Clinical Outcomes of Nonagenarian Compared with Octogenarian Acute Myocardial Infarction Patients Lee, Ki Hong Ahn, Youngkeun Kim, Sung Soo Rhew, Si Hyun Jeong, Young Wook Jang, Soo Young Cho, Jae Yeong Jeong, Hae Chang Park, Keun-Ho Yoon, Nam Sik Sim, Doo Sun Yoon, Hyun Joo Kim, Kye Hun Hong, Young Joon Park, Hyung Wook Kim, Ju Han Cho, Jeong Gwan Park, Jong Chun Jeong, Myung Ho Cho, Myeong-Chan Kim, Chong Jin Kim, Young Jo J Korean Med Sci Original Article We compared clinical characteristics, management, and clinical outcomes of nonagenarian acute myocardial infarction (AMI) patients (n=270, 92.3±2.3 yr old) with octogenarian AMI patients (n=2,145, 83.5±2.7 yr old) enrolled in Korean AMI Registry (KAMIR). Nonagenarians were less likely to have hypertension, diabetes and less likely to be prescribed with beta-blockers, statins, and glycoprotein IIb/IIIa inhibitors compared with octogenarians. Although percutaneous coronary intervention (PCI) was preferred in octogenarians than nonagenarians, the success rate of PCI between the two groups was comparable. In-hospital mortality, the composite of in-hospital adverse outcomes and one year mortality were higher in nonagenarians than in octogenarians. However, the composite of the one year major adverse cardiac events (MACEs) was comparable between the two groups without differences in MI or re-PCI rate. PCI improved 1-yr mortality (adjusted hazard ratio [HR], 0.50; 95% confidence interval [CI], 0.36-0.69, P<0.001) and MACEs (adjusted HR, 0.47; 95% CI, 0.37-0.61, P<0.001) without significant complications both in nonagenarians and octogenarians. In conclusion, nonagenarians had similar 1-yr MACEs rates despite of higher in-hospital and 1-yr mortality compared with octogenarian AMI patients. PCI in nonagenarian AMI patients was associated to better 1-yr clinical outcomes. GRAPHICAL ABSTRACT: [Image: see text] The Korean Academy of Medical Sciences 2014-04 2014-04-01 /pmc/articles/PMC3991796/ /pubmed/24753700 http://dx.doi.org/10.3346/jkms.2014.29.4.527 Text en © 2014 The Korean Academy of Medical Sciences. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Lee, Ki Hong
Ahn, Youngkeun
Kim, Sung Soo
Rhew, Si Hyun
Jeong, Young Wook
Jang, Soo Young
Cho, Jae Yeong
Jeong, Hae Chang
Park, Keun-Ho
Yoon, Nam Sik
Sim, Doo Sun
Yoon, Hyun Joo
Kim, Kye Hun
Hong, Young Joon
Park, Hyung Wook
Kim, Ju Han
Cho, Jeong Gwan
Park, Jong Chun
Jeong, Myung Ho
Cho, Myeong-Chan
Kim, Chong Jin
Kim, Young Jo
Characteristics, In-Hospital and Long-Term Clinical Outcomes of Nonagenarian Compared with Octogenarian Acute Myocardial Infarction Patients
title Characteristics, In-Hospital and Long-Term Clinical Outcomes of Nonagenarian Compared with Octogenarian Acute Myocardial Infarction Patients
title_full Characteristics, In-Hospital and Long-Term Clinical Outcomes of Nonagenarian Compared with Octogenarian Acute Myocardial Infarction Patients
title_fullStr Characteristics, In-Hospital and Long-Term Clinical Outcomes of Nonagenarian Compared with Octogenarian Acute Myocardial Infarction Patients
title_full_unstemmed Characteristics, In-Hospital and Long-Term Clinical Outcomes of Nonagenarian Compared with Octogenarian Acute Myocardial Infarction Patients
title_short Characteristics, In-Hospital and Long-Term Clinical Outcomes of Nonagenarian Compared with Octogenarian Acute Myocardial Infarction Patients
title_sort characteristics, in-hospital and long-term clinical outcomes of nonagenarian compared with octogenarian acute myocardial infarction patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991796/
https://www.ncbi.nlm.nih.gov/pubmed/24753700
http://dx.doi.org/10.3346/jkms.2014.29.4.527
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