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Single low-dose rHuIL-12 safely triggers multilineage hematopoietic and immune-mediated effects

BACKGROUND: Recombinant human interleukin 12 (rHuIL-12) regulates hematopoiesis and cell-mediated immunity. Based on these hematopoietic and immunomodulatory activities, a recombinant human IL-12 (rHuIL-12) is now under development to address the unmet need for a medical countermeasure against the h...

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Detalles Bibliográficos
Autores principales:	Gokhale, Mamata S, Vainstein, Vladimir, Tom, Jamie, Thomas, Simmy, Lawrence, Chris E, Gluzman-Poltorak, Zoya, Siebers, Nicholas, Basile, Lena A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991894/ https://www.ncbi.nlm.nih.gov/pubmed/24725395 http://dx.doi.org/10.1186/2162-3619-3-11

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