Cargando…

Study protocol of the RAND-study: a multicenter, prospective cohort study investigating response and adherence to nilotinib treatment in chronic myeloid leukemia

BACKGROUND: The antitumor drug nilotinib has a large inter- and intra individual variability in pharmacokinetics. Adherence to treatment may substantially influence plasma levels and has been recognized as the most important determinant of treatment failure in chronic myeloid leukemia (CML). A bette...

Descripción completa

Detalles Bibliográficos
Autores principales: Boons, Christel CLM, Swart, Eleonora L, Timmers, Lonneke, van de Ven, Peter M, Janssen, Jeroen JWM, Hugtenburg, Jacqueline G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991921/
https://www.ncbi.nlm.nih.gov/pubmed/24712728
http://dx.doi.org/10.1186/1471-2407-14-247