The emerging role of Nrf2 in dermatotoxicology

The nuclear factor erythroid 2-related factor 2 (Nrf2) is best known for its role in resistance to oxidant stress. In this issue of EMBO Molecular Medicine, Nrf2-prolonged genetic activation is shown with devastating effects on skin homeostasis. The study provides novel molecular insights into poiso...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Nguan S, Wahli, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Closeup
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992068/
https://www.ncbi.nlm.nih.gov/pubmed/24521743
http://dx.doi.org/10.1002/emmm.201303797
_version_ 1782312534754197504
author Tan, Nguan S
Wahli, Walter
author_facet Tan, Nguan S
Wahli, Walter
author_sort Tan, Nguan S
collection PubMed
description The nuclear factor erythroid 2-related factor 2 (Nrf2) is best known for its role in resistance to oxidant stress. In this issue of EMBO Molecular Medicine, Nrf2-prolonged genetic activation is shown with devastating effects on skin homeostasis. The study provides novel molecular insights into poison-induced chloracne and metabolizing acquired dioxin-induced skin hamartomas or MADISH.
format Online
Article
Text
id pubmed-3992068
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Blackwell Publishing Ltd
record_format MEDLINE/PubMed
spelling pubmed-39920682014-04-22 The emerging role of Nrf2 in dermatotoxicology Tan, Nguan S Wahli, Walter EMBO Mol Med Closeup The nuclear factor erythroid 2-related factor 2 (Nrf2) is best known for its role in resistance to oxidant stress. In this issue of EMBO Molecular Medicine, Nrf2-prolonged genetic activation is shown with devastating effects on skin homeostasis. The study provides novel molecular insights into poison-induced chloracne and metabolizing acquired dioxin-induced skin hamartomas or MADISH. Blackwell Publishing Ltd 2014-04 2014-02-12 /pmc/articles/PMC3992068/ /pubmed/24521743 http://dx.doi.org/10.1002/emmm.201303797 Text en © 2014 The Authors. http://creativecommons.org/licenses/by/3.0/ This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Closeup
Tan, Nguan S
Wahli, Walter
The emerging role of Nrf2 in dermatotoxicology
title The emerging role of Nrf2 in dermatotoxicology
title_full The emerging role of Nrf2 in dermatotoxicology
title_fullStr The emerging role of Nrf2 in dermatotoxicology
title_full_unstemmed The emerging role of Nrf2 in dermatotoxicology
title_short The emerging role of Nrf2 in dermatotoxicology
title_sort emerging role of nrf2 in dermatotoxicology
topic Closeup
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992068/
https://www.ncbi.nlm.nih.gov/pubmed/24521743
http://dx.doi.org/10.1002/emmm.201303797
work_keys_str_mv AT tannguans theemergingroleofnrf2indermatotoxicology
AT wahliwalter theemergingroleofnrf2indermatotoxicology
AT tannguans emergingroleofnrf2indermatotoxicology
AT wahliwalter emergingroleofnrf2indermatotoxicology

Ejemplares similares