Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion

Pancreatic cancer is characterised by desmoplasia, driven by activated pancreatic stellate cells (PSCs). Over-expression of FGFs and their receptors is a feature of pancreatic cancer and correlates with poor prognosis, but whether their expression impacts on PSCs is unclear. At the invasive front of...

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Detalles Bibliográficos
Autores principales: Coleman, Stacey J, Chioni, Athina-Myrto, Ghallab, Mohammed, Anderson, Rhys K, Lemoine, Nicholas R, Kocher, Hemant M, Grose, Richard P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Backwell Publishing Ltd 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992074/
https://www.ncbi.nlm.nih.gov/pubmed/24503018
http://dx.doi.org/10.1002/emmm.201302698

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