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PML-nuclear bodies decrease with age and their stress response is impaired in aged individuals
BACKGROUND: Promyelocytic leukemia nuclear bodies (PML-NBs) have been depicted as structures which are involved in processing cell damages and DNA double-strand break repairs. The study was designed to evaluate differences in patients’ PML-NBs response to stress factors like a cancerous disease and...
Autores principales: | Wenger, Barbara, Schwegler, Manuela, Brunner, Maria, Daniel, Christoph, Schmidt, Manfred, Fietkau, Rainer, Distel, Luitpold V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992156/ https://www.ncbi.nlm.nih.gov/pubmed/24694011 http://dx.doi.org/10.1186/1471-2318-14-42 |
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