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Effects of Preoperative Hypoxia on White Matter Injury Associated with Cardiopulmonary Bypass in a Rodent Hypoxic and Brain Slice Model
BACKGROUND: White matter (WM) injury is common after cardiopulmonary bypass or deep hypothermic circulatory arrest (DHCA) in neonates who have cerebral immaturity secondary to in utero hypoxia. The mechanism remains unknown. We investigated effects of preoperative-hypoxia on DHCA-induced WM-injury u...
Autores principales: | Agematsu, Kota, Korotcova, Ludmila, Scafidi, Joseph, Gallo, Vittorio, Jonas, Richard A., Ishibashi, Nobuyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992169/ https://www.ncbi.nlm.nih.gov/pubmed/24488087 http://dx.doi.org/10.1038/pr.2014.9 |
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