Leucine-rich repeat-containing G-protein-coupled receptor 5 is associated with invasion, metastasis, and could be a potential therapeutic target in human gastric cancer

BACKGROUND: Leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5), which is identified as a novel intestinal stem cell marker, is overexpressed in various tumours. In this study, we explore Lgr5 expression in gastric carcinoma and analyse its role in invasion, metastasis, and prognosis...

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Detalles Bibliográficos
Autores principales: Xi, H Q, Cai, A Z, Wu, X S, Cui, J X, Shen, W S, Bian, S B, Wang, N, Li, J Y, Lu, C R, Song, Z, Wei, B, Chen, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992491/
https://www.ncbi.nlm.nih.gov/pubmed/24594994
http://dx.doi.org/10.1038/bjc.2014.112

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