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Manipulating the expression of chemokine receptors enhances delivery and activity of cytokine-induced killer cells

BACKGROUND: Cytokine-induced killer (CIK) cells are ex vivo-expanded immune cells that express NK-cell and T-cell markers and that are routinely used in the treatment of many cancers. One key advantage of CIK cells is their ability to efficiently traffic to many solid tumours. Although likely to be...

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Detalles Bibliográficos
Autores principales: Zou, Y, Li, F, Hou, W, Sampath, P, Zhang, Y, Thorne, S H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992500/
https://www.ncbi.nlm.nih.gov/pubmed/24642619
http://dx.doi.org/10.1038/bjc.2014.140