LINE-1 methylation in leukocyte DNA, interaction with phosphatidylethanolamine N-methyltransferase variants and bladder cancer risk

BACKGROUND: Aberrant global DNA methylation is shown to increase cancer risk. LINE-1 has been proven a measure of global DNA methylation. The objectives of this study were to assess the association between LINE-1 methylation level and bladder cancer risk and to evaluate effect modification by enviro...

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Detalles Bibliográficos
Autores principales: Tajuddin, S M, Amaral, A F S, Fernández, A F, Chanock, S, Silverman, D T, Tardón, A, Carrato, A, García-Closas, M, Jackson, B P, Toraño, E G, Márquez, M, Urdinguio, R G, García-Closas, R, Rothman, N, Kogevinas, M, Real, F X, Fraga, M F, Malats, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Genetics & Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992509/
https://www.ncbi.nlm.nih.gov/pubmed/24595004
http://dx.doi.org/10.1038/bjc.2014.67

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