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Glutamate-based magnetic resonance spectroscopy in neuroleptic malignant syndrome
Glutamate neurotoxicity is implicated in a number of neurological diseases, including Neuroleptic Malignant syndrome. Therefore, functional magnetic resonance imaging can help in diagnosis and monitoring such conditions. However, reports of this application are scarce in the literature. In this manu...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992752/ https://www.ncbi.nlm.nih.gov/pubmed/24753679 http://dx.doi.org/10.4103/0972-2327.128579 |
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author | Chatterjee, Atri |
author_facet | Chatterjee, Atri |
author_sort | Chatterjee, Atri |
collection | PubMed |
description | Glutamate neurotoxicity is implicated in a number of neurological diseases, including Neuroleptic Malignant syndrome. Therefore, functional magnetic resonance imaging can help in diagnosis and monitoring such conditions. However, reports of this application are scarce in the literature. In this manuscript, glutamate based imaging of the basal ganglia showed increased levels of the neurotransmitter bilaterally. In addition, a radon transform of the functional image was performed to look for any asymmetry in cerebral activation. Although no asymmetry was detected in this case, this novel analysis can be applied in physiological and pathological scenarios to visualize contribution of different brain structures. |
format | Online Article Text |
id | pubmed-3992752 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-39927522014-04-21 Glutamate-based magnetic resonance spectroscopy in neuroleptic malignant syndrome Chatterjee, Atri Ann Indian Acad Neurol Case Report Glutamate neurotoxicity is implicated in a number of neurological diseases, including Neuroleptic Malignant syndrome. Therefore, functional magnetic resonance imaging can help in diagnosis and monitoring such conditions. However, reports of this application are scarce in the literature. In this manuscript, glutamate based imaging of the basal ganglia showed increased levels of the neurotransmitter bilaterally. In addition, a radon transform of the functional image was performed to look for any asymmetry in cerebral activation. Although no asymmetry was detected in this case, this novel analysis can be applied in physiological and pathological scenarios to visualize contribution of different brain structures. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC3992752/ /pubmed/24753679 http://dx.doi.org/10.4103/0972-2327.128579 Text en Copyright: © Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Chatterjee, Atri Glutamate-based magnetic resonance spectroscopy in neuroleptic malignant syndrome |
title | Glutamate-based magnetic resonance spectroscopy in neuroleptic malignant syndrome |
title_full | Glutamate-based magnetic resonance spectroscopy in neuroleptic malignant syndrome |
title_fullStr | Glutamate-based magnetic resonance spectroscopy in neuroleptic malignant syndrome |
title_full_unstemmed | Glutamate-based magnetic resonance spectroscopy in neuroleptic malignant syndrome |
title_short | Glutamate-based magnetic resonance spectroscopy in neuroleptic malignant syndrome |
title_sort | glutamate-based magnetic resonance spectroscopy in neuroleptic malignant syndrome |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992752/ https://www.ncbi.nlm.nih.gov/pubmed/24753679 http://dx.doi.org/10.4103/0972-2327.128579 |
work_keys_str_mv | AT chatterjeeatri glutamatebasedmagneticresonancespectroscopyinneurolepticmalignantsyndrome |