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Functional interpretation of non-coding sequence variation: Concepts and challenges

Understanding the functional mechanisms underlying genetic signals associated with complex traits and common diseases, such as cancer, diabetes and Alzheimer's disease, is a formidable challenge. Many genetic signals discovered through genome-wide association studies map to non-protein coding s...

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Detalles Bibliográficos
Autores principales:	Paul, Dirk S, Soranzo, Nicole, Beck, Stephan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY Periodicals, Inc. 2014
Materias:	Prospects & Overviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992842/ https://www.ncbi.nlm.nih.gov/pubmed/24311363 http://dx.doi.org/10.1002/bies.201300126

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