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Endothelin-1 directs airway remodeling and hyper-reactivity in a murine asthma model

BACKGROUND: The current paradigm describing asthma pathogenesis recognizes the central role of abnormal epithelial function in the generation and maintenance of the disease. However, the mechanisms responsible for the initiation of airway remodeling, which contributes to decreased lung function, rem...

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Detalles Bibliográficos
Autores principales:	Gregory, L G, Jones, C P, Mathie, S A, Pegorier, S, Lloyd, C M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Ltd 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992903/ https://www.ncbi.nlm.nih.gov/pubmed/24117726 http://dx.doi.org/10.1111/all.12271

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