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Rab8 Binding to Immune Cell-Specific Adaptor LAX Facilitates Formation of trans-Golgi Network-Proximal CTLA-4 Vesicles for Surface Expression

Despite playing a central role in tolerance, little is known regarding the mechanism by which intracellular CTLA-4 is shuttled from the trans-Golgi network to the surfaces of T cells. In this context, Ras-related GTPase Rab8 plays an important role in the intracellular transport, while we have previ...

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Detalles Bibliográficos
Autores principales:	Banton, Matthew C., Inder, Kerry L., Valk, Elke, Rudd, Christopher E., Schneider, Helga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993577/ https://www.ncbi.nlm.nih.gov/pubmed/24515439 http://dx.doi.org/10.1128/MCB.01331-13

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