Cargando…

A Concise Synthesis of Carolacton

[Image: see text] A synthesis of carolacton, a myxobacterial natural product that has profound effects on Streptococcus mutans biofilms, is reported. The synthesis proceeds via a longest linear sequence of 14 steps from an Evans β-ketoimide and enabled preliminary evaluations of the effects of late-...

Descripción completa

Detalles Bibliográficos
Autores principales: Hallside, Michal S., Brzozowski, Richard S., Wuest, William M., Phillips, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993612/
https://www.ncbi.nlm.nih.gov/pubmed/24483250
http://dx.doi.org/10.1021/ol500004k