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A Concise Synthesis of Carolacton
[Image: see text] A synthesis of carolacton, a myxobacterial natural product that has profound effects on Streptococcus mutans biofilms, is reported. The synthesis proceeds via a longest linear sequence of 14 steps from an Evans β-ketoimide and enabled preliminary evaluations of the effects of late-...
Autores principales: | Hallside, Michal S., Brzozowski, Richard S., Wuest, William M., Phillips, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993612/ https://www.ncbi.nlm.nih.gov/pubmed/24483250 http://dx.doi.org/10.1021/ol500004k |
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