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Activation of the Interferon Induction Cascade by Influenza A Viruses Requires Viral RNA Synthesis and Nuclear Export

We have examined the requirements for virus transcription and replication and thus the roles of input and progeny genomes in the generation of interferon (IFN)-inducing pathogen-associated molecular patterns (PAMPs) by influenza A viruses using inhibitors of these processes. Using IFN regulatory fac...

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Detalles Bibliográficos
Autores principales:	Killip, Marian J., Smith, Matt, Jackson, David, Randall, Richard E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2014
Materias:	Cellular Response to Infection
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993719/ https://www.ncbi.nlm.nih.gov/pubmed/24478437 http://dx.doi.org/10.1128/JVI.03109-13

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