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Novel Determinants of Antibiotic Resistance: Identification of Mutated Loci in Highly Methicillin-Resistant Subpopulations of Methicillin-Resistant Staphylococcus aureus

We identified mutated genes in highly resistant subpopulations of methicillin-resistant Staphylococcus aureus (MRSA) that are most likely responsible for the historic failure of the β-lactam family of antibiotics as therapeutic agents against these important pathogens. Such subpopulations are produc...

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Detalles Bibliográficos
Autores principales: Dordel, Janina, Kim, Choonkeun, Chung, Marilyn, Pardos de la Gándara, María, Holden, Matthew T. J., Parkhill, Julian, de Lencastre, Hermínia, Bentley, Stephen D., Tomasz, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993859/
https://www.ncbi.nlm.nih.gov/pubmed/24713324
http://dx.doi.org/10.1128/mBio.01000-13