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Dynamic, Nonsink Method for the Simultaneous Determination of Drug Permeability and Binding Coefficients in Liposomes
[Image: see text] Drug release from liposomal formulations is governed by a complex interplay of kinetic (i.e., drug permeability) and thermodynamic factors (i.e., drug partitioning to the bilayer surface). Release studies under sink conditions that attempt to mimic physiological conditions are insu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993891/ https://www.ncbi.nlm.nih.gov/pubmed/24628304 http://dx.doi.org/10.1021/mp400765n |