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Stilbenes as κ-Selective, Non-nitrogenous Opioid Receptor Antagonists
[Image: see text] The natural stilbene pawhuskin A has been shown to function as an opioid receptor antagonist, with preferential binding to the κ receptor. This finding encouraged assembly of a set of analogues to probe the importance of key structural features. Assays on these compounds determined...
Autores principales: | Hartung, Alyssa M., Beutler, John A., Navarro, Hernán A., Wiemer, David F., Neighbors, Jeffrey D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society and American
Society of Pharmacognosy
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993902/ https://www.ncbi.nlm.nih.gov/pubmed/24456556 http://dx.doi.org/10.1021/np4009046 |
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