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High-Affinity Recombinant Antibody Fragments (Fabs) Can Be Applied in Peptide Enrichment Immuno-MRM Assays
[Image: see text] High-affinity antibodies binding to linear peptides in solution are a prerequisite for performing immuno-MRM, an emerging technology for protein quantitation with high precision and specificity using peptide immunoaffinity enrichment coupled to stable isotope dilution and targeted...
Autores principales: | Whiteaker, Jeffrey R., Zhao, Lei, Frisch, Christian, Ylera, Francisco, Harth, Stefan, Knappik, Achim, Paulovich, Amanda G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993957/ https://www.ncbi.nlm.nih.gov/pubmed/24568200 http://dx.doi.org/10.1021/pr4009404 |
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