Cargando…

Gankyrin Is Frequently Overexpressed in Cervical High Grade Disease and Is Associated with Cervical Carcinogenesis and Metastasis

Our previous studies have showed that Gankyrin expression is correlated with a malignant phenotype in endometrial carcinoma. Here, we investigated the possible role of Gankyrin in cervical disease. The increasing protein level of Gankyrin was observed in high-grade cervical intraepithelial neoplasia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yuan, Zhang, Jiawen, Qian, Wenyan, Dong, Yu, Yang, Yongbin, Liu, Zhiqiang, Feng, Youji, Ma, Ding, Zhang, Zhenbo, Wu, Sufang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994022/ https://www.ncbi.nlm.nih.gov/pubmed/24751719 http://dx.doi.org/10.1371/journal.pone.0095043

Ejemplares similares

Gankyrin gene deletion followed by proteomic analysis: insight into the roles of Gankyrin in Tumorigenesis and Metastasis
por: Luo, Xue, et al.
Publicado: (2012)

LSD1 binds to HPV16 E7 and promotes the epithelial-mesenchymal transition in cervical cancer by demethylating histones at the Vimentin promoter
por: Liu, Yuan, et al.
Publicado: (2016)

Prognostic and clinicopathological significance of Gankyrin overexpression in cancers: evidence from a meta-analysis
por: Zhao, Xiaotong, et al.
Publicado: (2016)

Gankyrin activates the hedgehog signalling to drive metastasis in osteosarcoma
por: Wang, Chongchong, et al.
Publicado: (2021)

Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell
por: Chattopadhyay, Anasuya, et al.
Publicado: (2016)

The distribution and pathogenic risk of non‐9‐valent vaccine covered HPV subtypes in cervical lesions
por: Ma, Mingjun, et al.
Publicado: (2022)

Immune deviation and cervical carcinogenesis
por: Smola, Sigrun
Publicado: (2019)

LBH589 Inhibits proliferation and metastasis of hepatocellular carcinoma via inhibition of gankyrin/stat3/akt pathway
por: Song, Xuan, et al.
Publicado: (2013)

The long non-coding RNA Linc-GALH promotes hepatocellular carcinoma metastasis via epigenetically regulating Gankyrin
por: Xu, Xiaoliang, et al.
Publicado: (2019)

Gankyrin as Potential Biomarker for Colorectal Cancer With Occult Liver Metastases
por: Wang, Chengxing, et al.
Publicado: (2021)

Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma
por: Yang, Chun, et al.
Publicado: (2016)

Implications of tyrosine phosphoproteomics in cervical carcinogenesis
por: Robinson-Bennett, Bernice L, et al.
Publicado: (2008)

Aberrant DNA methylation in cervical Carcinogenesis
por: Yang, Hui-Juan
Publicado: (2013)

Cytokeratin7 and cytokeratin19 expression in high grade cervical intraepithelial neoplasm and squamous cell carcinoma and their possible association in cervical carcinogenesis
por: Lee, Hojung, et al.
Publicado: (2017)

The application of CRISPR/Cas9 system in cervical carcinogenesis
por: Gao, Chun, et al.
Publicado: (2021)

Resurfaced Shape Complementary Proteins That Selectively Bind the Oncoprotein Gankyrin
por: Chapman, Alex M., et al.
Publicado: (2014)

Gankyrin Drives Malignant Transformation of Gastric Cancer and Alleviates Oxidative Stress via mTORC1 Activation
por: Huang, Bo, et al.
Publicado: (2018)

Erratum to: Cytokeratin7 and cytokeratin19 expression in high grade cervical intraepithelial neoplasm and squamous cell carcinoma and their possible association in cervical carcinogenesis
por: Lee, Hojung, et al.
Publicado: (2017)

Paip1 Indicated Poor Prognosis in Cervical Cancer and Promoted Cervical Carcinogenesis
por: Li, Nan, et al.
Publicado: (2019)

Development of a Novel Immune Infiltration-Based Gene Signature to Predict Prognosis and Immunotherapy Response of Patients With Cervical Cancer
por: Yu, Sihui, et al.
Publicado: (2021)

Dysregulated tumor-associated macrophages in carcinogenesis, progression and targeted therapy of gynecological and breast cancers
por: Xu, Tianhan, et al.
Publicado: (2021)

Functional Role of NRF2 in Cervical Carcinogenesis
por: Ma, Jun-Qi, et al.
Publicado: (2015)

Gradually elevated expression of Gankyrin during human hepatocarcinogenesis and its clinicopathological significance
por: Jing, Hongbiao, et al.
Publicado: (2014)

Infiltration Patterns of Cervical Epithelial Microenvironment Cells During Carcinogenesis
por: Zhang, Jianwei, et al.
Publicado: (2022)

Frequent EGFR Positivity and Overexpression in High-Grade Areas of Human MPNSTs
por: Tabone-Eglinger, Séverine, et al.
Publicado: (2008)

KIFC1 regulated by miR-532-3p promotes epithelial-to-mesenchymal transition and metastasis of hepatocellular carcinoma via gankyrin/AKT signaling
por: Han, Jihua, et al.
Publicado: (2018)

FOXO3a loss is a frequent early event in high-grade pelvic serous carcinogenesis
por: Levanon, Keren, et al.
Publicado: (2013)

G6PC indicated poor prognosis in cervical cancer and promoted cervical carcinogenesis in vitro and in vivo
por: Zhu, Kun, et al.
Publicado: (2022)

Effects of Ligand Binding on the Mechanical Properties of Ankyrin Repeat Protein Gankyrin
por: Settanni, Giovanni, et al.
Publicado: (2013)

Gankyrin is a predictive and oncogenic factor in well-differentiated and dedifferentiated liposarcoma
por: Hwang, Ju-Ae, et al.
Publicado: (2014)

Gankyrin Promotes Tumor-Suppressor Protein Degradation to Drive Hepatocyte Proliferation
por: D’Souza, Amber M., et al.
Publicado: (2018)

High-sensitivity C-reactive Protein and Regression of Low-grade Squamous Intraepithelial Lesion: The Role of Low-grade Inflammation in Cervical Carcinogenesis
por: Ahn, Sangjeong, et al.
Publicado: (2021)

Overexpression of lncRNA H19 enhances carcinogenesis and metastasis of gastric cancer
por: Li, Hao, et al.
Publicado: (2014)

LMX1B-associated gankyrin expression predicts poor prognosis in glioma patients
por: Guo, Xu, et al.
Publicado: (2020)

Aberrant Hypermethylation of SALL3 with HPV Involvement Contributes to the Carcinogenesis of Cervical Cancer
por: Wei, Xing, et al.
Publicado: (2015)

ZNF671 methylation test in cervical scrapings for cervical intraepithelial neoplasia grade 3 and cervical cancer detection
por: Zhu, Peng, et al.
Publicado: (2023)

High Expression of PAMR1 Predicts Favorable Prognosis and Inhibits Proliferation, Invasion, and Migration in Cervical Cancer
por: Yang, Rui, et al.
Publicado: (2021)

The Immunological Contribution of a Novel Metabolism-Related Signature to the Prognosis and Anti-Tumor Immunity in Cervical Cancer
por: Yu, Sihui, et al.
Publicado: (2022)

Gankyrin is a novel biomarker for disease progression and prognosis of patients with renal cell carcinoma
por: Wang, Chao, et al.
Publicado: (2018)

Diagnostic importance of AgNOR pleomorphism in cervical carcinogenesis
por: Srivastava, AN, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_cauu11lgro9nv5p7p26khe32le