Sub-Inhibitory Fosmidomycin Exposures Elicits Oxidative Stress in Salmonella enterica Serovar typhimurium LT2

Fosmidomycin is a time-dependent nanomolar inhibitor of methylerythritol phosphate (MEP) synthase, which is the enzyme that catalyzes the first committed step in the MEP pathway to isoprenoids. Importantly, fosmidomycin is one of only a few MEP pathway-specific inhibitors that exhibits antimicrobial...

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Detalles Bibliográficos
Autores principales: Fox, David T., Schmidt, Emily N., Tian, Hongzhao, Dhungana, Suraj, Valentine, Michael C., Warrington, Nicole V., Phillips, Paul D., Finney, Kellan B., Cope, Emily K., Leid, Jeff G., Testa, Charles A., Koppisch, Andrew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994034/
https://www.ncbi.nlm.nih.gov/pubmed/24751777
http://dx.doi.org/10.1371/journal.pone.0095271

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