Formation of a Polarised Primitive Endoderm Layer in Embryoid Bodies Requires Fgfr/Erk Signalling

The primitive endoderm arises from the inner cell mass during mammalian pre-implantation development. It faces the blastocoel cavity and later gives rise to the extraembryonic parietal and visceral endoderm. Here, we investigate a key step in primitive endoderm development, the acquisition of apico-...

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Detalles Bibliográficos
Autores principales: Doughton, Gail, Wei, Jun, Tapon, Nicolas, Welham, Melanie J., Chalmers, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994041/
https://www.ncbi.nlm.nih.gov/pubmed/24752320
http://dx.doi.org/10.1371/journal.pone.0095434

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