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HD CAGnome: A Search Tool for Huntingtin CAG Repeat Length-Correlated Genes

BACKGROUND: The length of the huntingtin (HTT) CAG repeat is strongly correlated with both age at onset of Huntington’s disease (HD) symptoms and age at death of HD patients. Dichotomous analysis comparing HD to controls is widely used to study the effects of HTT CAG repeat expansion. However, a pot...

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Detalles Bibliográficos
Autores principales: Galkina, Ekaterina I., Shin, Aram, Coser, Kathryn R., Shioda, Toshi, Kohane, Isaac S., Seong, Ihn Sik, Wheeler, Vanessa C., Gusella, James F., MacDonald, Marcy E., Lee, Jong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994101/
https://www.ncbi.nlm.nih.gov/pubmed/24751919
http://dx.doi.org/10.1371/journal.pone.0095556