Alcohol Enhances Acinetobacter baumannii-Associated Pneumonia and Systemic Dissemination by Impairing Neutrophil Antimicrobial Activity in a Murine Model of Infection

Acinetobacter baumannii (Ab) is a common cause of community-acquired pneumonia (CAP) in chronic alcoholics in tropical and sub-tropical climates and associated with a >50% mortality rate. Using a murine model of alcohol (EtOH) administration, we demonstrated that EtOH enhances Ab-mediated pneumon...

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Detalles Bibliográficos
Autores principales: Gandhi, Jay A., Ekhar, Vaibhav V., Asplund, Melissa B., Abdulkareem, Asan F., Ahmadi, Mohammed, Coelho, Carolina, Martinez, Luis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994102/
https://www.ncbi.nlm.nih.gov/pubmed/24752133
http://dx.doi.org/10.1371/journal.pone.0095707

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