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Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein

Cystic fibrosis (CF) is a fatal genetic disease caused by mutations in the CFTR (cystic fibrosis transmembrane conductance regulator) gene that regulates chloride and water transport across all epithelia and affects multiple organs including the lungs. Here we report an in vitro directed differentia...

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Detalles Bibliográficos
Autores principales:	Wong, Amy P., Bear, Christine E., Chin, Stephanie, Pasceri, Peter, Thompson, Tadeo O., Huan, Ling-Jun, Ratjen, Felix, Ellis, James, Rossant, Janet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994104/ https://www.ncbi.nlm.nih.gov/pubmed/22922672 http://dx.doi.org/10.1038/nbt.2328

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