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Trypanosoma cruzi Infection Down-Modulates the Immunoproteasome Biosynthesis and the MHC Class I Cell Surface Expression in HeLa Cells

Generally, Trypanosoma cruzi infection in human is persistent and tends to chronicity, suggesting that the parasite evade the immune surveillance by down regulating the intracellular antigen processing routes. Within the MHC class I pathway, the majority of antigenic peptides are generated by the pr...

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Detalles Bibliográficos
Autores principales: Camargo, Ricardo, Faria, Liliam O., Kloss, Alexander, Favali, Cecília B. F., Kuckelkorn, Ulrike, Kloetzel, Peter-Michael, de Sá, Cezar Martins, Lima, Beatriz D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994161/
https://www.ncbi.nlm.nih.gov/pubmed/24752321
http://dx.doi.org/10.1371/journal.pone.0095977