Evidence of excretion of Schmallenberg virus in bull semen

Schmallenberg virus (SBV) is a novel orthobunyavirus, discovered in Germany in late 2011. It mainly infects cattle, sheep and goats and could lead to congenital infection, causing abortion and fetal abnormalities. SBV is transmitted by biting midges from the Culicoides genus and there is no evidence...

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Autores principales: Ponsart, Claire, Pozzi, Nathalie, Bréard, Emmanuel, Catinot, Virginie, Viard, Guillaume, Sailleau, Corinne, Viarouge, Cyril, Gouzil, Julie, Beer, Martin, Zientara, Stéphan, Vitour, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994198/
https://www.ncbi.nlm.nih.gov/pubmed/24708245
http://dx.doi.org/10.1186/1297-9716-45-37
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author Ponsart, Claire
Pozzi, Nathalie
Bréard, Emmanuel
Catinot, Virginie
Viard, Guillaume
Sailleau, Corinne
Viarouge, Cyril
Gouzil, Julie
Beer, Martin
Zientara, Stéphan
Vitour, Damien
author_facet Ponsart, Claire
Pozzi, Nathalie
Bréard, Emmanuel
Catinot, Virginie
Viard, Guillaume
Sailleau, Corinne
Viarouge, Cyril
Gouzil, Julie
Beer, Martin
Zientara, Stéphan
Vitour, Damien
author_sort Ponsart, Claire
collection PubMed
description Schmallenberg virus (SBV) is a novel orthobunyavirus, discovered in Germany in late 2011. It mainly infects cattle, sheep and goats and could lead to congenital infection, causing abortion and fetal abnormalities. SBV is transmitted by biting midges from the Culicoides genus and there is no evidence that natural infection occurs directly between ruminants. Here, we could detect SBV RNA in infected bull semen using qRT-PCR (three bulls out of seven tested positive; 29 positive semen batches out of 136). We also found that highly positive semen batches from SBV infected bulls can provoke an acute infection in IFNAR(-/-) mice, suggesting the potential presence of infectious virus in the semen of SBV infected bulls.
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spelling pubmed-39941982014-04-23 Evidence of excretion of Schmallenberg virus in bull semen Ponsart, Claire Pozzi, Nathalie Bréard, Emmanuel Catinot, Virginie Viard, Guillaume Sailleau, Corinne Viarouge, Cyril Gouzil, Julie Beer, Martin Zientara, Stéphan Vitour, Damien Vet Res Short Report Schmallenberg virus (SBV) is a novel orthobunyavirus, discovered in Germany in late 2011. It mainly infects cattle, sheep and goats and could lead to congenital infection, causing abortion and fetal abnormalities. SBV is transmitted by biting midges from the Culicoides genus and there is no evidence that natural infection occurs directly between ruminants. Here, we could detect SBV RNA in infected bull semen using qRT-PCR (three bulls out of seven tested positive; 29 positive semen batches out of 136). We also found that highly positive semen batches from SBV infected bulls can provoke an acute infection in IFNAR(-/-) mice, suggesting the potential presence of infectious virus in the semen of SBV infected bulls. BioMed Central 2014 2014-04-04 /pmc/articles/PMC3994198/ /pubmed/24708245 http://dx.doi.org/10.1186/1297-9716-45-37 Text en Copyright © 2014 Ponsart et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Short Report
Ponsart, Claire
Pozzi, Nathalie
Bréard, Emmanuel
Catinot, Virginie
Viard, Guillaume
Sailleau, Corinne
Viarouge, Cyril
Gouzil, Julie
Beer, Martin
Zientara, Stéphan
Vitour, Damien
Evidence of excretion of Schmallenberg virus in bull semen
title Evidence of excretion of Schmallenberg virus in bull semen
title_full Evidence of excretion of Schmallenberg virus in bull semen
title_fullStr Evidence of excretion of Schmallenberg virus in bull semen
title_full_unstemmed Evidence of excretion of Schmallenberg virus in bull semen
title_short Evidence of excretion of Schmallenberg virus in bull semen
title_sort evidence of excretion of schmallenberg virus in bull semen
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994198/
https://www.ncbi.nlm.nih.gov/pubmed/24708245
http://dx.doi.org/10.1186/1297-9716-45-37
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