Fractionated radiotherapy is the main stimulus for the induction of cell death and of Hsp70 release of p53 mutated glioblastoma cell lines

BACKGROUND: Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults. Despite a multimodal therapy consisting of resection followed by fractionated radiotherapy (RT) combined with the chemotherapeutic agent (CT) temozolomide (TMZ), its recurrence is almost inevitable. Since the...

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Detalles Bibliográficos
Autores principales: Rubner, Yvonne, Muth, Carolin, Strnad, Annedore, Derer, Anja, Sieber, Renate, Buslei, Rolf, Frey, Benjamin, Fietkau, Rainer, Gaipl, Udo S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994240/
https://www.ncbi.nlm.nih.gov/pubmed/24678590
http://dx.doi.org/10.1186/1748-717X-9-89

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