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A new in situ hybridization and immunohistochemistry with a novel antibody to detect small T-antigen expressions of Merkel cell polyomavirus (MCPyV)

BACKGROUND: Approximately 80% of Merkel cell carcinomas (MCCs) harbor Merkel cell polyomavirus (MCPyV) which monoclonally integrates into the genome and has prognostic significance. The presence or absence of MCPyV is usually diagnosed using CM2B4 immunohistochemistry (IHC) for MCPyV-large T antigen...

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Detalles Bibliográficos
Autores principales:	Matsushita, Michiko, Nonaka, Daisuke, Iwasaki, Takeshi, Kuwamoto, Satoshi, Murakami, Ichiro, Kato, Masako, Nagata, Keiko, Kitamura, Yukisato, Hayashi, Kazuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994555/ https://www.ncbi.nlm.nih.gov/pubmed/24649978 http://dx.doi.org/10.1186/1746-1596-9-65

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