Cargando…
The statistical interpretation of pilot trials: should significance thresholds be reconsidered?
BACKGROUND: In an evaluation of a new health technology, a pilot trial may be undertaken prior to a trial that makes a definitive assessment of benefit. The objective of pilot studies is to provide sufficient evidence that a larger definitive trial can be undertaken and, at times, to provide a preli...
Autores principales: | Lee, Ellen C, Whitehead, Amy L, Jacques, Richard M, Julious, Steven A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994566/ https://www.ncbi.nlm.nih.gov/pubmed/24650044 http://dx.doi.org/10.1186/1471-2288-14-41 |
Ejemplares similares
-
Guidance for using pilot studies to inform the design of intervention trials with continuous outcomes
por: Bell, Melanie L, et al.
Publicado: (2018) -
Estimating the sample size for a pilot randomised trial to minimise the overall trial sample size for the external pilot and main trial for a continuous outcome variable
por: Whitehead, Amy L, et al.
Publicado: (2015) -
Reconsidering the conventional interpretation of the uncertainty relations
por: Dumitru, S
Publicado: (2000) -
Do pilot trials reliably predict recruitment and retention rates for full trial? A review of HTA funded trials
por: Whitehead, Amy, et al.
Publicado: (2015) -
An audit of sample sizes for pilot and feasibility trials being undertaken in the United Kingdom registered in the United Kingdom Clinical Research Network database
por: Billingham, Sophie AM, et al.
Publicado: (2013)