Long-term follow-up in two cases of intracranial Rosai–Dorfman Disease complicated by incomplete resection and recurrence

BACKGROUND: Although intracranial Rosai–Dorfman disease is a principally benign lymphohistiocytosis, some patients run a relapsing or progressive course. However, reports about long-term follow-up are extremely rare. CASE DESCRIPTION: In two patients, initial tumor resection was incomplete or follow...

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Autores principales: Rivera, Diones, Pérez-Castillo, Miguelina, Fernández, Belkis, Stoeter, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994694/
https://www.ncbi.nlm.nih.gov/pubmed/24778918
http://dx.doi.org/10.4103/2152-7806.128003
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author Rivera, Diones
Pérez-Castillo, Miguelina
Fernández, Belkis
Stoeter, Peter
author_facet Rivera, Diones
Pérez-Castillo, Miguelina
Fernández, Belkis
Stoeter, Peter
author_sort Rivera, Diones
collection PubMed
description BACKGROUND: Although intracranial Rosai–Dorfman disease is a principally benign lymphohistiocytosis, some patients run a relapsing or progressive course. However, reports about long-term follow-up are extremely rare. CASE DESCRIPTION: In two patients, initial tumor resection was incomplete or followed by recurrences over 3 years, which finally subsided after application of chemotherapy, and patients remained tumor-free for more than 7 years thereafter. CONCLUSION: Up to now there is no agreement on how to treat complicated cases of intracranial Rosai–Dorfman disease; our good experience with adjuvant chemotherapy and long-term follow-up will contribute to treatment planning in complicated cases.
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spelling pubmed-39946942014-04-28 Long-term follow-up in two cases of intracranial Rosai–Dorfman Disease complicated by incomplete resection and recurrence Rivera, Diones Pérez-Castillo, Miguelina Fernández, Belkis Stoeter, Peter Surg Neurol Int Case Report BACKGROUND: Although intracranial Rosai–Dorfman disease is a principally benign lymphohistiocytosis, some patients run a relapsing or progressive course. However, reports about long-term follow-up are extremely rare. CASE DESCRIPTION: In two patients, initial tumor resection was incomplete or followed by recurrences over 3 years, which finally subsided after application of chemotherapy, and patients remained tumor-free for more than 7 years thereafter. CONCLUSION: Up to now there is no agreement on how to treat complicated cases of intracranial Rosai–Dorfman disease; our good experience with adjuvant chemotherapy and long-term follow-up will contribute to treatment planning in complicated cases. Medknow Publications & Media Pvt Ltd 2014-02-28 /pmc/articles/PMC3994694/ /pubmed/24778918 http://dx.doi.org/10.4103/2152-7806.128003 Text en Copyright: © 2014 Rivera D. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Rivera, Diones
Pérez-Castillo, Miguelina
Fernández, Belkis
Stoeter, Peter
Long-term follow-up in two cases of intracranial Rosai–Dorfman Disease complicated by incomplete resection and recurrence
title Long-term follow-up in two cases of intracranial Rosai–Dorfman Disease complicated by incomplete resection and recurrence
title_full Long-term follow-up in two cases of intracranial Rosai–Dorfman Disease complicated by incomplete resection and recurrence
title_fullStr Long-term follow-up in two cases of intracranial Rosai–Dorfman Disease complicated by incomplete resection and recurrence
title_full_unstemmed Long-term follow-up in two cases of intracranial Rosai–Dorfman Disease complicated by incomplete resection and recurrence
title_short Long-term follow-up in two cases of intracranial Rosai–Dorfman Disease complicated by incomplete resection and recurrence
title_sort long-term follow-up in two cases of intracranial rosai–dorfman disease complicated by incomplete resection and recurrence
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994694/
https://www.ncbi.nlm.nih.gov/pubmed/24778918
http://dx.doi.org/10.4103/2152-7806.128003
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AT fernandezbelkis longtermfollowupintwocasesofintracranialrosaidorfmandiseasecomplicatedbyincompleteresectionandrecurrence
AT stoeterpeter longtermfollowupintwocasesofintracranialrosaidorfmandiseasecomplicatedbyincompleteresectionandrecurrence

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