Giant clival chordoma causing pathological laughter

BACKGROUND: Chordomas are rare slowly growing tumors that originate from remnants of the notochord. They have a malignant local behavior, causing symptoms due to bone infiltration and compression of neurovascular structures. Only a few cases of brain tumors associated with pathological laughter have...

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Detalles Bibliográficos
Autores principales: Gripp, Daniel Andrade, do Souto, Antonio Aversa, Gonsales, Douglas, Christiani, Marcio de Miranda Chaves, Nogueira, Janio, Lopes, Helio Ferreira, Torres, Yasmine Coura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994695/
https://www.ncbi.nlm.nih.gov/pubmed/24778906
http://dx.doi.org/10.4103/2152-7806.127257
Descripción
Sumario:BACKGROUND: Chordomas are rare slowly growing tumors that originate from remnants of the notochord. They have a malignant local behavior, causing symptoms due to bone infiltration and compression of neurovascular structures. Only a few cases of brain tumors associated with pathological laughter have been reported in the literature. CASE DESCRIPTION: We report a case of a 42-year-old male patient with this atypical clinical presentation treated at our institution, and discuss the concerning literature. CONCLUSION: Although being a very rare presentation of chordomas, pathological laughter is usually expected to improve after brain stem decompression.

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