Giant clival chordoma causing pathological laughter

BACKGROUND: Chordomas are rare slowly growing tumors that originate from remnants of the notochord. They have a malignant local behavior, causing symptoms due to bone infiltration and compression of neurovascular structures. Only a few cases of brain tumors associated with pathological laughter have...

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Autores principales: Gripp, Daniel Andrade, do Souto, Antonio Aversa, Gonsales, Douglas, Christiani, Marcio de Miranda Chaves, Nogueira, Janio, Lopes, Helio Ferreira, Torres, Yasmine Coura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994695/
https://www.ncbi.nlm.nih.gov/pubmed/24778906
http://dx.doi.org/10.4103/2152-7806.127257
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author Gripp, Daniel Andrade
do Souto, Antonio Aversa
Gonsales, Douglas
Christiani, Marcio de Miranda Chaves
Nogueira, Janio
Lopes, Helio Ferreira
Torres, Yasmine Coura
author_facet Gripp, Daniel Andrade
do Souto, Antonio Aversa
Gonsales, Douglas
Christiani, Marcio de Miranda Chaves
Nogueira, Janio
Lopes, Helio Ferreira
Torres, Yasmine Coura
author_sort Gripp, Daniel Andrade
collection PubMed
description BACKGROUND: Chordomas are rare slowly growing tumors that originate from remnants of the notochord. They have a malignant local behavior, causing symptoms due to bone infiltration and compression of neurovascular structures. Only a few cases of brain tumors associated with pathological laughter have been reported in the literature. CASE DESCRIPTION: We report a case of a 42-year-old male patient with this atypical clinical presentation treated at our institution, and discuss the concerning literature. CONCLUSION: Although being a very rare presentation of chordomas, pathological laughter is usually expected to improve after brain stem decompression.
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spelling pubmed-39946952014-04-28 Giant clival chordoma causing pathological laughter Gripp, Daniel Andrade do Souto, Antonio Aversa Gonsales, Douglas Christiani, Marcio de Miranda Chaves Nogueira, Janio Lopes, Helio Ferreira Torres, Yasmine Coura Surg Neurol Int Case Report BACKGROUND: Chordomas are rare slowly growing tumors that originate from remnants of the notochord. They have a malignant local behavior, causing symptoms due to bone infiltration and compression of neurovascular structures. Only a few cases of brain tumors associated with pathological laughter have been reported in the literature. CASE DESCRIPTION: We report a case of a 42-year-old male patient with this atypical clinical presentation treated at our institution, and discuss the concerning literature. CONCLUSION: Although being a very rare presentation of chordomas, pathological laughter is usually expected to improve after brain stem decompression. Medknow Publications & Media Pvt Ltd 2014-02-17 /pmc/articles/PMC3994695/ /pubmed/24778906 http://dx.doi.org/10.4103/2152-7806.127257 Text en Copyright: © 2014 Gripp DA. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Gripp, Daniel Andrade
do Souto, Antonio Aversa
Gonsales, Douglas
Christiani, Marcio de Miranda Chaves
Nogueira, Janio
Lopes, Helio Ferreira
Torres, Yasmine Coura
Giant clival chordoma causing pathological laughter
title Giant clival chordoma causing pathological laughter
title_full Giant clival chordoma causing pathological laughter
title_fullStr Giant clival chordoma causing pathological laughter
title_full_unstemmed Giant clival chordoma causing pathological laughter
title_short Giant clival chordoma causing pathological laughter
title_sort giant clival chordoma causing pathological laughter
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994695/
https://www.ncbi.nlm.nih.gov/pubmed/24778906
http://dx.doi.org/10.4103/2152-7806.127257
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