Cargando…
Neutralizing Th2 Inflammation in Neonatal Islets Prevents β-Cell Failure in Adult IUGR Rats
Intrauterine growth restriction (IUGR) leads to development of type 2 diabetes (T2D) in adulthood. The mechanisms underlying this phenomenon have not been fully elucidated. Inflammation is associated with T2D; however, it is unknown whether inflammation is causal or secondary to the altered metaboli...
Autores principales: | Jaeckle Santos, Lane J., Li, Changhong, Doulias, Paschalis-Thomas, Ischiropoulos, Harry, Worthen, G. Scott, Simmons, Rebecca A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994952/ https://www.ncbi.nlm.nih.gov/pubmed/24408314 http://dx.doi.org/10.2337/db13-1226 |
Ejemplares similares
-
Reducing Th2 inflammation through neutralizing IL-4 antibody rescues myelination in IUGR rat brain
por: Zanno, Allison E., et al.
Publicado: (2019) -
Islet inflammation is associated with pancreatic fatty infiltration and hyperglycemia in type 2 diabetes
por: Horii, Tomomi, et al.
Publicado: (2020) -
Vascular Endothelial Growth Factor–Mediated Islet Hypervascularization and Inflammation Contribute to Progressive Reduction of β-Cell Mass
por: Agudo, Judith, et al.
Publicado: (2012) -
Intracutaneous Transplantation of Islets Within a Biodegradable Temporizing Matrix as an Alternative Site for Islet Transplantation
por: Rojas-Canales, Darling, et al.
Publicado: (2023) -
Somatostatin Secreted by Islet δ-Cells Fulfills Multiple Roles as a Paracrine Regulator of Islet Function
por: Hauge-Evans, Astrid C., et al.
Publicado: (2009)