Preserved Energy Balance in Mice Lacking FoxO1 in Neurons of Nkx2.1 Lineage Reveals Functional Heterogeneity of FoxO1 Signaling Within the Hypothalamus

Transcription factor forkhead box O1 (FoxO1) regulates energy expenditure (EE), food intake, and hepatic glucose production. These activities have been mapped to specific hypothalamic neuronal populations using cell type–specific knockout experiments in mice. To parse out the integrated output of Fo...

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Detalles Bibliográficos
Autores principales: Heinrich, Garrett, Meece, Kana, Wardlaw, Sharon L., Accili, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994959/
https://www.ncbi.nlm.nih.gov/pubmed/24487022
http://dx.doi.org/10.2337/db13-0651

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