Cargando…

Alternative Polyadenylation of Tumor Suppressor Genes in Small Intestinal Neuroendocrine Tumors

The tumorigenesis of small intestinal neuroendocrine tumors (SI-NETs) is poorly understood. Recent studies have associated alternative polyadenylation (APA) with proliferation, cell transformation, and cancer. Polyadenylation is the process in which the pre-messenger RNA is cleaved at a polyA site a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rehfeld, Anders, Plass, Mireya, Døssing, Kristina, Knigge, Ulrich, Kjær, Andreas, Krogh, Anders, Friis-Hansen, Lennart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995063/ https://www.ncbi.nlm.nih.gov/pubmed/24782827 http://dx.doi.org/10.3389/fendo.2014.00046

Ejemplares similares

Alterations in Polyadenylation and Its Implications for Endocrine Disease
por: Rehfeld, Anders, et al.
Publicado: (2013)

Down-Regulation of miR-129-5p and the let-7 Family in Neuroendocrine Tumors and Metastases Leads to Up-Regulation of Their Targets Egr1, G3bp1, Hmga2 and Bach1
por: Døssing, Kristina B. V., et al.
Publicado: (2014)

Somatostatin Analogue Treatment Primarily Induce miRNA Expression Changes and Up-Regulates Growth Inhibitory miR-7 and miR-148a in Neuroendocrine Cells
por: Døssing, Kristina B. V., et al.
Publicado: (2018)

Use of radioactive substances in diagnosis and treatment of neuroendocrine tumors
por: Kjaer, Andreas, et al.
Publicado: (2015)

Limited Diagnostic Utility of Chromogranin A Measurements in Workup of Neuroendocrine Tumors
por: Baekdal, Jonas, et al.
Publicado: (2020)

Predicting Progression, Recurrence, and Survival in Pancreatic Neuroendocrine Tumors: A Single Center Analysis of 174 Patients
por: Krogh, Sara, et al.
Publicado: (2022)

Incidence, Clinical Presentation and Trends in Indication for Diagnostic Work-Up of Small Intestinal and Pancreatic Neuroendocrine Tumors
por: Stensbøl, Anna Bryan, et al.
Publicado: (2021)

Widespread intronic polyadenylation inactivates tumor suppressor genes in leukemia
por: Lee, Shih-Han, et al.
Publicado: (2018)

Plasma protein biomarkers for the detection of pancreatic neuroendocrine tumors and differentiation from small intestinal neuroendocrine tumors
por: Thiis‐Evensen, Espen, et al.
Publicado: (2022)

(18)F-FDG and (18)F-FLT-PET Imaging for Monitoring Everolimus Effect on Tumor-Growth in Neuroendocrine Tumors: Studies in Human Tumor Xenografts in Mice
por: Bardram Johnbeck, Camilla, et al.
Publicado: (2014)

PTEN: Tumor Suppressor and Metabolic Regulator
por: Chen, Chien-Yu, et al.
Publicado: (2018)

Long-term organoid culture of a small intestinal neuroendocrine tumor
por: D’Agosto, Sabrina, et al.
Publicado: (2023)

Epigenetic regulation of SST(2) expression in small intestinal neuroendocrine tumors
por: Klomp, Maria J., et al.
Publicado: (2023)

Clinical Epigenetics of Neuroendocrine Tumors: The Road Ahead
por: Colao, Annamaria, et al.
Publicado: (2020)

Editorial: Neuroendocrine tumors: the road to precision medicine
por: La Salvia, Anna, et al.
Publicado: (2023)

Cowden Syndrome and Concomitant Pulmonary Neuroendocrine Tumor: A Presentation of Two Cases
por: Langer, Seppo W., et al.
Publicado: (2015)

Highly accessible AU-rich regions in 3’ untranslated regions are hotspots for binding of regulatory factors
por: Plass, Mireya, et al.
Publicado: (2017)

Overlooked FANCD2 variant encodes a promising, portent tumor suppressor, and alternative polyadenylation contributes to its expression
por: Han, Bing, et al.
Publicado: (2017)

Clinical and Preclinical Advances in Gastroenteropancreatic Neuroendocrine Tumor Therapy
por: Crabtree, Judy S.
Publicado: (2017)

Molecular Signatures and Their Clinical Utility in Pancreatic Neuroendocrine Tumors
por: Chatani, Praveen Dilip, et al.
Publicado: (2021)

Psychological distress and resilience in patients with gastroenteropancreatic neuroendocrine tumor
por: Song, Lili, et al.
Publicado: (2022)

CFIm25 links Alternative Polyadenylation to Glioblastoma Tumor Suppression
por: Masamha, Chioniso P., et al.
Publicado: (2014)

IGF-Binding Protein 2 – Oncogene or Tumor Suppressor?
por: Pickard, Adam, et al.
Publicado: (2015)

The p53 Tumor Suppressor in the Control of Metabolism and Ferroptosis
por: Gnanapradeepan, Keerthana, et al.
Publicado: (2018)

Bisphenol A Diglycidyl Ether (BADGE) and Bisphenol Analogs, but Not Bisphenol A (BPA), Activate the CatSper Ca(2+) Channel in Human Sperm
por: Rehfeld, Anders, et al.
Publicado: (2020)

mTOR Pathway in Gastroenteropancreatic Neuroendocrine Tumor (GEP-NETs)
por: Zanini, Sara, et al.
Publicado: (2020)

Ex Vivo Modeling of Human Neuroendocrine Tumors in Tissue Surrogates
por: Herring, Brendon, et al.
Publicado: (2021)

Case Report: Re-Treatment With Lu-DOTATATE in Neuroendocrine Tumors
por: Vida Navas, Elena María, et al.
Publicado: (2021)

Pseudocapsule and pseudocapsule-based extracapsular resection in pituitary neuroendocrine tumors
por: Wang, Xiao Bin, et al.
Publicado: (2022)

Nomogram for preoperative estimation of histologic grade in gastrointestinal neuroendocrine tumors
por: Wu, Zhi-Qi, et al.
Publicado: (2022)

The evolution of PRRT for the treatment of neuroendocrine tumors; What comes next?
por: Harris, Philip E., et al.
Publicado: (2022)

Identification of the enhancer RNAs related to tumorgenesis of pituitary neuroendocrine tumors
por: Wang, Liangbo, et al.
Publicado: (2023)

Induction of Anti-Tumor Immune Responses by Peptide Receptor Radionuclide Therapy with (177)Lu-DOTATATE in a Murine Model of a Human Neuroendocrine Tumor
por: Wu, Yin, et al.
Publicado: (2013)

Cleavage and Polyadenylation Specific Factor 1 Promotes Tumor Progression via Alternative Polyadenylation and Splicing in Hepatocellular Carcinoma
por: Chen, Shi-lu, et al.
Publicado: (2021)

PTPRM, a candidate tumor suppressor gene in small intestinal neuroendocrine tumors
por: Barazeghi, Elham, et al.
Publicado: (2019)

Recurrent tumor-specific regulation of alternative polyadenylation of cancer-related genes
por: Xue, Zhuyi, et al.
Publicado: (2018)

Relationship between NUDT21 mediated alternative polyadenylation process and tumor
por: Xiao, Shan, et al.
Publicado: (2023)

Octreotide Does Not Inhibit Proliferation in Five Neuroendocrine Tumor Cell Lines
por: Exner, Samantha, et al.
Publicado: (2018)

Progress in the Pathogenesis, Diagnosis, and Treatment of TSH-Secreting Pituitary Neuroendocrine Tumor
por: Luo, Peiqiong, et al.
Publicado: (2020)

Role of Somatostatin Receptor in Pancreatic Neuroendocrine Tumor Development, Diagnosis, and Therapy
por: Hu, Yuheng, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_bral5i8kve642dci5nlnv6ttk1