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Treatment of medulloblastoma with oncolytic measles viruses expressing the angiogenesis inhibitors endostatin and angiostatin
BACKGROUND: Medulloblastoma is the most common type of pediatric brain tumor. Although numerous factors influence patient survival rates, more than 30% of all cases will ultimately be refractory to conventional therapies. Current standards of care are also associated with significant morbidities, gi...
Autores principales: | Hutzen, Brian, Bid, Hemant Kumar, Houghton, Peter J, Pierson, Christopher R, Powell, Kimerly, Bratasz, Anna, Raffel, Corey, Studebaker, Adam W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995427/ https://www.ncbi.nlm.nih.gov/pubmed/24646176 http://dx.doi.org/10.1186/1471-2407-14-206 |
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