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Increased diacylglycerol kinase ζ expression in human metastatic colon cancer cells augments Rho GTPase activity and contributes to enhanced invasion
BACKGROUND: Unraveling the signaling pathways responsible for the establishment of a metastatic phenotype in carcinoma cells is critically important for understanding the pathology of cancer. The acquisition of cell motility is a key property of metastatic tumor cells and is a prerequisite for invas...
Autores principales: | Cai, Kun, Mulatz, Kirk, Ard, Ryan, Nguyen, Thanh, Gee, Stephen H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995506/ https://www.ncbi.nlm.nih.gov/pubmed/24646293 http://dx.doi.org/10.1186/1471-2407-14-208 |
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