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Expression and activity of Rac1 is negatively affected in the dehydroepiandrosterone induced polycystic ovary of mouse

BACKGROUND: Polycystic ovarian syndrome (PCOS) is characterized by the presence of multiple follicular cysts, giving rise to infertility due to anovulation. This syndrome affects about 10% of women, worldwide. The exact molecular mechanism leading to PCOS remains obscure. RhoGTPase has been associat...

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Detalles Bibliográficos
Autores principales: Maurya, Vineet Kumar, Sangappa, Chadchan, Kumar, Vijay, Mahfooz, Sahil, Singh, Archana, Rajender, Singh, Jha, Rajesh Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995551/
https://www.ncbi.nlm.nih.gov/pubmed/24628852
http://dx.doi.org/10.1186/1757-2215-7-32

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