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Independent absorbed-dose calculation using the Monte Carlo algorithm in volumetric modulated arc therapy

PURPOSE: To report the result of independent absorbed-dose calculations based on a Monte Carlo (MC) algorithm in volumetric modulated arc therapy (VMAT) for various treatment sites. METHODS AND MATERIALS: All treatment plans were created by the superposition/convolution (SC) algorithm of SmartArc (P...

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Autores principales: Haga, Akihiro, Magome, Taiki, Takenaka, Shigeharu, Imae, Toshikazu, Sakumi, Akira, Nomoto, Akihiro, Igaki, Hiroshi, Shiraishi, Kenshiro, Yamashita, Hideomi, Ohtomo, Kuni, Nakagawa, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995553/
https://www.ncbi.nlm.nih.gov/pubmed/24625221
http://dx.doi.org/10.1186/1748-717X-9-75
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author Haga, Akihiro
Magome, Taiki
Takenaka, Shigeharu
Imae, Toshikazu
Sakumi, Akira
Nomoto, Akihiro
Igaki, Hiroshi
Shiraishi, Kenshiro
Yamashita, Hideomi
Ohtomo, Kuni
Nakagawa, Keiichi
author_facet Haga, Akihiro
Magome, Taiki
Takenaka, Shigeharu
Imae, Toshikazu
Sakumi, Akira
Nomoto, Akihiro
Igaki, Hiroshi
Shiraishi, Kenshiro
Yamashita, Hideomi
Ohtomo, Kuni
Nakagawa, Keiichi
author_sort Haga, Akihiro
collection PubMed
description PURPOSE: To report the result of independent absorbed-dose calculations based on a Monte Carlo (MC) algorithm in volumetric modulated arc therapy (VMAT) for various treatment sites. METHODS AND MATERIALS: All treatment plans were created by the superposition/convolution (SC) algorithm of SmartArc (Pinnacle V9.2, Philips). The beam information was converted into the format of the Monaco V3.3 (Elekta), which uses the X-ray voxel-based MC (XVMC) algorithm. The dose distribution was independently recalculated in the Monaco. The dose for the planning target volume (PTV) and the organ at risk (OAR) were analyzed via comparisons with those of the treatment plan. Before performing an independent absorbed-dose calculation, the validation was conducted via irradiation from 3 different gantry angles with a 10- × 10-cm(2) field. For the independent absorbed-dose calculation, 15 patients with cancer (prostate, 5; lung, 5; head and neck, 3; rectal, 1; and esophageal, 1) who were treated with single-arc VMAT were selected. To classify the cause of the dose difference between the Pinnacle and Monaco TPSs, their calculations were also compared with the measurement data. RESULT: In validation, the dose in Pinnacle agreed with that in Monaco within 1.5%. The agreement in VMAT calculations between Pinnacle and Monaco using phantoms was exceptional; at the isocenter, the difference was less than 1.5% for all the patients. For independent absorbed-dose calculations, the agreement was also extremely good. For the mean dose for the PTV in particular, the agreement was within 2.0% in all the patients; specifically, no large difference was observed for high-dose regions. Conversely, a significant difference was observed in the mean dose for the OAR. For patients with prostate cancer, the mean rectal dose calculated in Monaco was significantly smaller than that calculated in Pinnacle. CONCLUSIONS: There was no remarkable difference between the SC and XVMC calculations in the high-dose regions. The difference observed in the low-dose regions may have arisen from various causes such as the intrinsic dose deviation in the MC calculation, modeling accuracy, and CT-to-density table used in each planning system It is useful to perform independent absorbed-dose calculations with the MC algorithm in intensity-modulated radiation therapy commissioning.
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spelling pubmed-39955532014-04-23 Independent absorbed-dose calculation using the Monte Carlo algorithm in volumetric modulated arc therapy Haga, Akihiro Magome, Taiki Takenaka, Shigeharu Imae, Toshikazu Sakumi, Akira Nomoto, Akihiro Igaki, Hiroshi Shiraishi, Kenshiro Yamashita, Hideomi Ohtomo, Kuni Nakagawa, Keiichi Radiat Oncol Research PURPOSE: To report the result of independent absorbed-dose calculations based on a Monte Carlo (MC) algorithm in volumetric modulated arc therapy (VMAT) for various treatment sites. METHODS AND MATERIALS: All treatment plans were created by the superposition/convolution (SC) algorithm of SmartArc (Pinnacle V9.2, Philips). The beam information was converted into the format of the Monaco V3.3 (Elekta), which uses the X-ray voxel-based MC (XVMC) algorithm. The dose distribution was independently recalculated in the Monaco. The dose for the planning target volume (PTV) and the organ at risk (OAR) were analyzed via comparisons with those of the treatment plan. Before performing an independent absorbed-dose calculation, the validation was conducted via irradiation from 3 different gantry angles with a 10- × 10-cm(2) field. For the independent absorbed-dose calculation, 15 patients with cancer (prostate, 5; lung, 5; head and neck, 3; rectal, 1; and esophageal, 1) who were treated with single-arc VMAT were selected. To classify the cause of the dose difference between the Pinnacle and Monaco TPSs, their calculations were also compared with the measurement data. RESULT: In validation, the dose in Pinnacle agreed with that in Monaco within 1.5%. The agreement in VMAT calculations between Pinnacle and Monaco using phantoms was exceptional; at the isocenter, the difference was less than 1.5% for all the patients. For independent absorbed-dose calculations, the agreement was also extremely good. For the mean dose for the PTV in particular, the agreement was within 2.0% in all the patients; specifically, no large difference was observed for high-dose regions. Conversely, a significant difference was observed in the mean dose for the OAR. For patients with prostate cancer, the mean rectal dose calculated in Monaco was significantly smaller than that calculated in Pinnacle. CONCLUSIONS: There was no remarkable difference between the SC and XVMC calculations in the high-dose regions. The difference observed in the low-dose regions may have arisen from various causes such as the intrinsic dose deviation in the MC calculation, modeling accuracy, and CT-to-density table used in each planning system It is useful to perform independent absorbed-dose calculations with the MC algorithm in intensity-modulated radiation therapy commissioning. BioMed Central 2014-03-14 /pmc/articles/PMC3995553/ /pubmed/24625221 http://dx.doi.org/10.1186/1748-717X-9-75 Text en Copyright © 2014 Haga et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Haga, Akihiro
Magome, Taiki
Takenaka, Shigeharu
Imae, Toshikazu
Sakumi, Akira
Nomoto, Akihiro
Igaki, Hiroshi
Shiraishi, Kenshiro
Yamashita, Hideomi
Ohtomo, Kuni
Nakagawa, Keiichi
Independent absorbed-dose calculation using the Monte Carlo algorithm in volumetric modulated arc therapy
title Independent absorbed-dose calculation using the Monte Carlo algorithm in volumetric modulated arc therapy
title_full Independent absorbed-dose calculation using the Monte Carlo algorithm in volumetric modulated arc therapy
title_fullStr Independent absorbed-dose calculation using the Monte Carlo algorithm in volumetric modulated arc therapy
title_full_unstemmed Independent absorbed-dose calculation using the Monte Carlo algorithm in volumetric modulated arc therapy
title_short Independent absorbed-dose calculation using the Monte Carlo algorithm in volumetric modulated arc therapy
title_sort independent absorbed-dose calculation using the monte carlo algorithm in volumetric modulated arc therapy
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995553/
https://www.ncbi.nlm.nih.gov/pubmed/24625221
http://dx.doi.org/10.1186/1748-717X-9-75
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