Cargando…

Nanoscale changes in chromatin organization represent the initial steps of tumorigenesis: a transmission electron microscopy study

BACKGROUND: Nuclear alterations are a well-known manifestation of cancer. However, little is known about the early, microscopically-undetectable stages of malignant transformation. Based on the phenomenon of field cancerization, the tissue in the field of a tumor can be used to identify and study th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cherkezyan, Lusik, Stypula-Cyrus, Yolanda, Subramanian, Hariharan, White, Craig, Dela Cruz, Mart, Wali, Ramesh K, Goldberg, Michael J, Bianchi, Laura K, Roy, Hemant K, Backman, Vadim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995586/ https://www.ncbi.nlm.nih.gov/pubmed/24629088 http://dx.doi.org/10.1186/1471-2407-14-189

Ejemplares similares

HDAC Up-Regulation in Early Colon Field Carcinogenesis Is Involved in Cell Tumorigenicity through Regulation of Chromatin Structure
por: Stypula-Cyrus, Yolanda, et al.
Publicado: (2013)

The transformation of the nuclear nanoarchitecture in human field carcinogenesis
por: Bauer, Greta M, et al.
Publicado: (2017)

Dysregulation of MicroRNAs in Colonic Field Carcinogenesis: Implications for Screening
por: Kunte, Dhananjay P., et al.
Publicado: (2012)

Early screening of colorectal cancer using feature engineering with artificial intelligence-enhanced analysis of nanoscale chromatin modifications
por: Chang, Andrew, et al.
Publicado: (2023)

Early screening of colorectal cancer using feature engineering with artificial intelligence-enhanced analysis of nanoscale chromatin modifications
por: Chang, Andrew, et al.
Publicado: (2023)

Biophotonic detection of high order chromatin alterations in field carcinogenesis predicts risk of future hepatocellular carcinoma: A pilot study
por: Kalman, Richard, et al.
Publicado: (2018)

Correction: Biophotonic detection of high order chromatin alterations in field carcinogenesis predicts risk of future hepatocellular carcinoma: A pilot study
por: Kalman, Richard S., et al.
Publicado: (2018)

The Global Relationship between Chromatin Physical Topology, Fractal Structure, and Gene Expression
por: Almassalha, L. M., et al.
Publicado: (2017)

Preservation of cellular nano-architecture by the process of chemical fixation for nanopathology
por: Zhou, Xiang, et al.
Publicado: (2019)

Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm
por: Gladstein, Scott, et al.
Publicado: (2019)

Biological Mechanisms Underlying Structural Changes Induced by Colorectal Field Carcinogenesis Measured with Low-Coherence Enhanced Backscattering (LEBS) Spectroscopy
por: Mutyal, Nikhil N., et al.
Publicado: (2013)

Early detection of lung cancer using artificial intelligence-enhanced optical nanosensing of chromatin alterations in field carcinogenesis
por: Daneshkhah, Ali, et al.
Publicado: (2023)

Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis
por: Cruz, Mart Dela, et al.
Publicado: (2017)

Buccal microRNA dysregulation in lung field carcinogenesis: Gender-specific implications
por: WALI, RAMESH K., et al.
Publicado: (2014)

Linker histones are fine-scale chromatin architects modulating developmental decisions in Arabidopsis
por: Rutowicz, Kinga, et al.
Publicado: (2019)

Nanoscale chromatin imaging and analysis platform bridges 4D chromatin organization with molecular function
por: Li, Yue, et al.
Publicado: (2021)

Evidence for possible association of vitamin D status with cytokine storm and unregulated inflammation in COVID-19 patients
por: Daneshkhah, Ali, et al.
Publicado: (2020)

Correlating colorectal cancer risk with field carcinogenesis progression using partial wave spectroscopic microscopy
por: Gladstein, Scott, et al.
Publicado: (2018)

Chromatin hierarchical branching visualized at the nanoscale by electron microscopy
por: Zhou, Zhongwu, et al.
Publicado: (2020)

Depth-resolved measurement of mucosal microvascular blood content using  low-coherence enhanced backscattering spectroscopy
por: Radosevich, Andrew J., et al.
Publicado: (2010)

Disordered chromatin packing regulates phenotypic plasticity
por: Virk, Ranya K. A., et al.
Publicado: (2020)

Automated Cell Selection Using Support Vector Machine for Application to Spectral Nanocytology
por: Miao, Qin, et al.
Publicado: (2016)

Advances in Biophotonics Detection of Field Carcinogenesis for Colon Cancer Risk Stratification
por: Backman, Vadim, et al.
Publicado: (2013)

Chromatin and Cancer: Implications of Disrupted Chromatin Organization in Tumorigenesis and Its Diversification
por: Sehgal, Poonam, et al.
Publicado: (2023)

Epigenetic condensates regulate chromatin activity and tumorigenesis
por: Shi, Bi, et al.
Publicado: (2021)

Investigating Population Risk Factors of Pancreatic Cancer by Evaluation of Optical Markers in the Duodenal Mucosa
por: Turzhitsky, Vladimir, et al.
Publicado: (2008)

Investigating Population Risk Factors of Pancreatic Cancer by Evaluation of Optical Markers in the Duodenal Mucosa
por: Turzhitsky, Vladimir, et al.
Publicado: (2009)

Differences in nanoscale organization of regulatory active and inactive human chromatin
por: Brandstetter, Katharina, et al.
Publicado: (2022)

Investigation of depth-resolved nanoscale structural changes in regulated cell proliferation and chromatin decondensation
por: Uttam, Shikhar, et al.
Publicado: (2013)

Prevention of colonic neoplasia with polyethylene glycol: A short term randomized placebo-controlled double-blinded trial
por: Wali, Ramesh K., et al.
Publicado: (2018)

Single Nucleotide Polymorphism Facilitated Down-Regulation of the Cohesin Stromal Antigen-1: Implications for Colorectal Cancer Racial Disparities
por: Datta, Somenath, et al.
Publicado: (2018)

Interplay among ATP-Dependent Chromatin Remodelers Determines Chromatin Organisation in Yeast
por: Prajapati, Hemant K., et al.
Publicado: (2020)

ATRX Links Chromatin Remodeling to Inflammation and Tumorigenesis in the Pancreas
por: Means, Anna L.
Publicado: (2018)

Chromatin and noncoding RNA-mediated mechanisms of gastric tumorigenesis
por: Loe, Adrian Kwan Ho, et al.
Publicado: (2023)

Oncogenic signaling-mediated regulation of chromatin during tumorigenesis
por: Alam, Jahangir, et al.
Publicado: (2023)

Chromatin as self-returning walks: From population to single cell and back
por: Shim, Anne R., et al.
Publicado: (2021)

Formation of correlated chromatin domains at nanoscale dynamic resolution during transcription
por: Shaban, Haitham A, et al.
Publicado: (2018)

Chromatin arranges in chains of mesoscale domains with nanoscale functional topography independent of cohesin
por: Miron, Ezequiel, et al.
Publicado: (2020)

Fast and parallel nanoscale three-dimensional tracking of heterogeneous mammalian chromatin dynamics
por: Gustavsson, Anna-Karin, et al.
Publicado: (2022)

Nanocytological Field Carcinogenesis Detection to Mitigate Overdiagnosis of Prostate Cancer: A Proof of Concept Study
por: Roy, Hemant K., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_3c4vrrgde9cnm3mk800horgbql