Epidermal growth factor receptor gene polymorphisms are associated with prognostic features of breast cancer

BACKGROUND: The epidermal growth factor receptor (EGFR) is differently expressed in breast cancer, and its presence may favor cancer progression. We hypothesized that two EGFR functional polymorphisms, a (CA)n repeat in intron 1, and a single nucleotide polymorphism, R497K, may affect EGFR expressio...

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Detalles Bibliográficos
Autores principales: Leite, Marcelo Sobral, Giacomin, Letícia Carlos, Piranda, Diogo Nascimento, Festa-Vasconcellos, Juliana Simões, Indio-do-Brasil, Vanessa, Koifman, Sérgio, de Moura-Neto, Rodrigo Soares, de Carvalho, Marcelo Alex, Vianna-Jorge, Rosane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995591/
https://www.ncbi.nlm.nih.gov/pubmed/24629097
http://dx.doi.org/10.1186/1471-2407-14-190

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